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Prevalence and Associated factors of Antiepileptic Drug Non-Adherence among Epileptic Patients Attending at outpatient Department of Hiwot Fana Specialized University Hospital, Harar, Eastern Ethiopia

Sudhen sumesh kumar, Kabtamu Nigussie, Rebira Beyene, Netsant Ayele

Abstract


Background: Antiepileptic drugs were effective in the treatment of epilepsy, but non-adherence to medication was major problem to sustained remission and to functional restoration, non-adherence of epileptic patients to antiepileptic medication was one of many reasons for pharmacological treatment failure, death, increased heath care costs and seizure recurrence. Even though there were studies on the magnitude and associated factors of antiepileptic drugs non-adherence, there was a shortage of published information regarding the prevalence and associated factors of Antiepileptic drugs non-adherence in Ethiopia. Objective: To assess the prevalence and associated factors of antiepileptic drug no adherence among epileptic patients attending at Hiwot Fana Specialized University Hospital, Eastern Ethiopia. Methods: Institution based cross-sectional study design was conducted at Hiwot Fana Specialized University Hospital from February 24 to April 7, 2017. A total of 140 individuals were selected by consecutive sampling technique and interviewed by using interviewer administered structured questionnaire. Morisky 8-items Medication Adherence Scale was used to assess the prevalence of antiepileptic drug non-adherence. Data were coded and would be exported to SPSS version 20 for analysis. Data was collected from February 24 to April 7, 2017. By investigators after obtain consent from participants. Result: The prevalence of antiepileptic drug non-adherence in this study was 36.03% and ever skipped dose [AOR=0.005, 95%, CI: 0.015, 0.16] getting medication by payment [AOR 2.009, 95%, CI: 1.044, 3.868], poor social support [AOR= 0.126, 95%, CI: 0.0310, .508], and patients duration of treatment greater or equal to six years [AOR=0.240, 95%, CI: 0.06, 0.967] were found to be significantly associated with antiepileptic drugs (p). Conclusion: The prevalence of antiepileptic drug non-adherences among epileptic patient was relatively equal with that done at Jimma Referral Hospital. Skip dose, duration of treatment greater or equal six years, getting medication by payment, poor social support were found to be the independent predictor of antiepileptic drugs (AEDs) non-adherence.

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DOI: https://doi.org/10.37628/ijnn.v5i1.1028

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