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Systematic Review on Helicobacter pylori Infection and Risk of Lung Cancer

Kripa Angeline


Background: Lung cancer kills more people worldwide (over 1 million each year) than any other cancer lung cancer is the second most common cancer in both men and women. Helicobacter pylori seropositivity is a risk factor for lung, gastric and several other cancers. An increased seroprevalence was also found in various respiratory diseases like chronic bronchitis, asthma, and pulmonary tuberculosis. Methods: A search was conducted to identify the eligible published articles, based upon the predefined inclusion exclusion criteria. Each article was independently reviewed. The body of evidence for association between H. plylori and lung cancer was assigned a level of evidence, based on previously published criteria. Results: The literature search identified 30 papers, and a detailed evaluation was done based on titles and abstracts. Of these, 20 papers qualified for final inclusion in the systematic reviews. The association between H. plylori and lung cancer was established This article describes the association between lung cancer and risk factor. Conclusions: The association between H. plylori and lung cancer will enable to treat and correct the risk factor at the earliest for lung cancer

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