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COVID 19 ASSOCIATED MUCORMYCOSIS (BLACK FUNGUS)

REJANI R

Abstract


Mucormycosis is an infection caused by a group of filamentous moulds within the order Mucorales.
Infections may result from ingestion of contaminated food, inhalation of spores into the nares or
lungs, or inoculation into disrupted skin or wounds. In developed countries, mucormycosis occurs
primarily in severely immunocompromised hosts. Only 6 to 10% of cases occur in subjects with no
underlying disease. In contrast, in developing countries, most cases of mucormycosis occur in persons
with poorly controlled diabetes mellitus or in immunocompetent subjects following trauma.
Mucormycosis exhibits a marked propensity to invade blood vessels, leading to thrombosis, necrosis,
and infarction of tissue.


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References


Song G, Liang G, Liu W. Fungal co-infections associated with global COVID-19 pandemic: a

clinical and diagnostic perspective from China. Mycopathologia. 2020; 185(4): 599–606.

Garg D, Muthu V, Sehgal IS, Ramachandran R, Kaur H, Bhalla A, Puri GD, Chakrabarti A,

Agarwal R. Coronavirus disease (COVID-19) associated mucormycosis (CAM): case report and

systematic review of literature. Mycopathologia. 2021; 186(2): 289–298.

Prakash H, Ghosh AK, Rudramurthy SM, Singh P, Xess I, Savio J, Pamidimukkala U, Jillwin J,

Varma S, Das A, Panda NK. A prospective multicenter study on mucormycosis in India:

Epidemiology, diagnosis, and treatment. Med Mycol. 2019; 57(4): 395–402.

Spellberg B, Edwards Jr J, Ibrahim A. Novel perspectives on mucormycosis: pathophysiology,

presentation, and management. Clinical Microbiol Rev. 2005; 18(3): 556–569.

Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and

clinical manifestations of mucormycosis. Clin Infect Dis. 2012 Feb 1; 54(suppl_1): S23–34.

Skiada A, Pavleas I, Drogari-Apiranthitou M. Epidemiology and diagnosis of mucormycosis: an

update. J Fungi. 2020; 6(4): 265.

Katragkou A, Walsh TJ, Roilides E. Why is mucormycosis more difficult to cure than more

common mycoses? Clin Microbiol Infect. 2014; 20(Suppl 6): 74–81.

Lin E, Moua T, Limper AH. Pulmonary mucormycosis: clinical features and outcomes. Infection.

; 45(4): 443–448.

Farmakiotis D, Kontoyiannis DP. Mucormycoses. Infect Dis Clin North Am. 2016; 30(1):

–63.

Sahota R, Gambhir R, Anand S, Dixit A. Rhinocerebral mucormycosis: report of a rare case.

Ethiop J Health Sci. 2017; 27(1): 85–90.




DOI: https://doi.org/10.37628/ijin.v8i1.2035

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