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PRION DISEASES: A RARE NEURO-GENERATIVE DEVELOPING DISORDERS

Shivaraj S Annigeri, Ananda Kudari, Sumangala B R

Abstract


Prion diseases are rare, rapidly progressive, fatal neurodegenerative developing diseases affecting in both humans and animals with longer incubation period. These prion diseases are caused by unknown cause, iatrogenic transmission like direct intracerebral injection, prion infected organ transplantation and contact with prion infected feces of animals with scrapie. The clinical finding with prion diseases is that dementia and other neuro muscular symptoms. It is diagnosed by lumbar puncture, magnetic resonance imaging, and Real-time quaking-induced conversion (RT-QuIC). There is no known treatment and cure for prion disease, but it has preventive measures symptomatic treatment to make patient comfortable like opiate, sedative, ant seizer for pain and involuntary movements.


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References


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DOI: https://doi.org/10.37628/ijnn.v8i1.2085

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